Hexaene H-85, a hexaene macrolide complex.
نویسندگان
چکیده
منابع مشابه
Hexaene H-85, a hexaene macrolide complex.
The hexaene macrolide antibiotics constitute the smallest group of the polyenes (12 ~ 1 5). Mediocidin, endomycin, hexaene H-85 and hexafungin each have a significant tetraene spectrum in addition to a hexaene spectrum (hexaene spectrum being predominant) and show high activity against fungi and moderate against Gram-positive bacteria. It was not possible to isolate the separate tetraene and he...
متن کاملThe influence of Schiff base inclusion complexes with β-cyclodextrine on antibiotic production by Streptomyces hygroscopicus CH-7
A media consisting of isatin-Schiff bases and its inclusion complexes with β-cyclodextrine was developed to maximize the production of antibiotics Hexaene H-85 and azalomycine B by Streptomyces hygroscopicus CH-7. The media with β-cyclodextrine inclusion complex of isatin-3-thiosemicarbazone resulted in the maximum antibiotics concentration of 493 μg/cm for Hexaene H-85 and 191 μg/cm for azalom...
متن کامل3,6,14,17-Tetramethoxy-22,23-diphenyl-1,10,12,21-tetraazahexacyclo[19.2.1.02,7.010,23.012,22.013,18]tetracosa-2(7),3,5,13(18),14,16-hexaene-11,24-dithione
The title compound, C(36)H(34)N(4)O(4)S(2), is a thio-glycoluril derivative, which bears two phenyl substituents on its convex face and two meth-oxy substituted o-xylylenes as sidewalls of the molecular clip. There is one half-mol-ecule in the asymmetric unit: a crystallographic twofold axis generates the complete molecule. The non-planar seven-membered rings adopt chair conformations, while th...
متن کاملIsolation, purification and properties of the hexaene macrolides candihexin I and candihexin II.
The hexaene macrolide candihexin produced by the mutant 18A2 of Streptomyces viridoflavus IMRU 3685 has been found to be a complex of two component fractions which we have named candihexins I and II. Extraction and purification methods have been developed for preparation of pure candihexin complex. Separation of the component fractions has been achieved by solvent fractionation and partition co...
متن کاملThe impact of different carbon and nitrogen sources on antibiotic production by Streptomyces hygroscopicus CH-7
The effects of the composition and rheology of the fermentation medium on the antibiotic production by Streptomyces hygroscopicus CH-7 were studied. To increase the yields of hexaene H-85 and elaiophylin, the basic fermentation medium was reformulated using different carbon (glucose, lactose, ribose, fructose and trehalose) and nitrogen (isatin-Schiff bases) sources. The maximum yields of hexae...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1991
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.44.1452